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administration of 50 and 100 mg/kg SNS-314 Mesylate results a dose-dependent inhibition of histone H3 phosphorylation
InChiKey: RAHBGWKEPAQNFF-UHFFFAOYSA-N
Chemical Name: sodium 3-[(3
It inhibits Ack1 and germinal center kinase (GCK)
Hydralazine Hydrochloride atinine administration of 50 and 100Hydralazine Hydrochloride is a direct acting vasodilator that is used as an antihypertensive agent. Hydralazine Hydrochloride alters intracellular calcium release and interferes with smooth muscle cell calcium influx, resulting in arterial vasodilatation. This agent also inhibits the phosphorylation of myosin protein and chelation of trace metals required for smooth muscle contraction, resulting in an increase in heart rate, stroke volume and cardiac
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